Human Autoimmune Diseases - 1086 Words

Abstract—Immune system failure can cause many human autoimmune diseases which make body produce antibodies in the blood which attack human antigens not foreign antigens and it can cause many serious and chronic illnesses. This phenomenon results in an auto-immune response which generate the auto-antibodies (ANAs) during this response. This auto-antibodies (ANAs) may be identified through the indirect immunofluorescence test (IIF). But unfortunately, today the IIF is still a subjective method as well as time and labor intensive. Thus, to address these problems, computer Aided Diagnostic (CAD) systems have been developed which automatically classify a human epithelial cells type-2 (HEp-2) cell images into one of its known patterns. This†¦show more content†¦Then, check them under a fluorescence microscope after adding a fluorescence tag which binds to the antibodies according to the type of present antibodies. Hep-2 cells take one of six different patterns which are: ho mogeneous, fine speckled and coarse speckled, centromere, nuclear, cytoplasmic [6]. However, IIF is a subjective method in discovering immune diseases, it depends too seriously on the experience of physicians and unfortunately the accuracy of inter-laboratories agreement drops to 76% for recognition of stained patterns which require more detailed diagnosis [7]. This drops is due to many reasons like the Quantitative information which supplied to physicians are not enough, reading from systems and optics are varying from each other, irradiation occurred through the photo-bleaching effect caused by the light [8] and the reproducibility of the diagnostic protocol is low [9]. In recent years, for these reasons and more there has been increasing interest in employing various image analysis techniques for classification of HEP-2 cells images. Many CAD systems which have been proposed in this field are concerned with shape and morphological features [10-23]. Cordelli et al. [11] consider a heterogeneous set of texture features belonging to different categories, statistical descriptors, spectral measures, local binary pattern (LBP) and morphological descriptors.Show MoreRelatedCoexistence of Autoimmune Disease with Type I Diabetes Mellitus in Libyan Patients2041 Words   |  8 PagesMATERIAL AND METHODS The prospective clinical study was undertaken on 849 patients admitted in endocrine department of Tripoli Medical Center from December 2007 to July 2008. From the patients files, the concomitant disease presence or absence was also recorded; especially with reference thyroid function. The important investigations as prescribed by the physician were also recorded. patient’s serum level of T4, T3, FT4, FT3 and TSH were measured for 748 patients. The venous blood samples wereRead MoreNaturally Occurring T Regulatory Cells, Interleukins 10 and 12 in the Pathogenesis of Idiopathic Warm Autoimmune Hemolytic Anemia.3975 Words   |  16 PagesABSTRACT There is now compelling evidence from animal models autoimmune hemolytic anemia (AIHA) that naturally occurring regulatory T cells (n-Tregs) play an important role in immunologic tolerance and control of immune-mediated pathology. However their study in human AIHA is still ill defined. Aim: To measure the peripheral blood proportions of n-Treg cells and the levels of IL10 and IL12 in basal and mitogen-induced (Lipopolysaccharide, LPS) cultures of PBMCs in patients with idiopathic warmRead MoreAre Autoimmune Diseases Killing You?803 Words   |  4 PagesAre Autoimmune Diseases Killing You? The innate/adaptive immune systems are supposed to protect you – what happens when they strike back? 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A recentRead MoreAutoimmune Disease : Autoimmune Diseases Essay1315 Words   |  6 Pages Autoimmune diseases are a growing concern in the American population. An estimated 10 million Americans suffer from autoimmune diseases with 75% of these cases being of women. Furthermore, autoimmune diseases have grown to be within the top 10 causes of death among American women. The incidences of these diseases have been shown to increase with financial wealth, industrial development, and the modern progression of life. As such, the occurrence of these conditions is expected to grow as time passesRead More Eliminating Obesity and Autoimmune Disease Essay example1691 Words   |  7 Pagesfoods we consider healthy actually that? What is the diet that will alleviate the problems of obesity and autoimmune disease? Each has a very simple and sensible answer. Obesity and autoimmune disease may be considered the scourge of the modern western world. It is very interesting however, that other cultures with different diets, either do not have our obesity and autoimmune diseases, or are slowly following our trend (meaning the problems we have had since the invention of agriculture, otherRead MoreEssay about The Hygiene Hypothesis1083 Words   |  5 Pagesstates that although we have shifted rapidly into a clean, modern and civilized state, our bodies have not yet adapted, and our immune system is responding inappropriately with an increased susceptibility to allergies and autoimmune diseases. The main premise is that humans are mismatched to modernity. (Stearns, 2009) Our civilization has changed rapidly and we now readily have access to modern hygiene, clean water, and antibiotics but our bodies have not yet evolved to adapt with its new environmentRead MoreThe Way the Immune System Works Essay1507 Words   |  7 PagesTHE IMMUNE SYSTEM Definition of the Immune System The human immune system is a collective network of tissues, glands, and organs that work in a coordinated effort with each other to guard our bodies from foreign antigens such as viruses, bacteria, and infection causing microorganisms. For the immune system to work properly, two things must happen: first, the body must recognize that it has been invaded, either by pathogens or toxins or by some other threat. Second, the immune response must beRead MoreAutoimmune Disease By Vitamin D. D ) Case Study1070 Words   |  5 PagesThis important molecule is naturally occurs in all human cells12. Production of this cell is through the conversion of the amino acid tryptophan or vitamin B3, although it turns out vitamin B3 has one significant drawback12. And as we age, the metabolic activity in human body gets slow down. As due to less production of this molecule in the human body, there will be the less production of fuel energy production and immune system regulation as well12. Many years back, researchers observed NAD+ isRead MoreCase Study of Graves Disease Essay1639 Words   |  7 Pages Introduction The case study selected focused on Grave’s disease an autoimmune disorder involving over production of thyroid hormones triidiothyronine (T3) and thyroxine (T4). In the United States it is the most common form of hyperthyroidism. The over taxed organ then becomes enlarged (goiter). This case study report will discuss the clinical progression and presentation of this disease, define and describe what an autoimmune disorder is, outline what clinical testing is performed for proper diagnosis

The Truth About Behavior, Emotions And Emotional Intelligence

The Truth About Behaviour, Emotions and Emotional Intelligence After over 10 years in studying human behaviour from the psychological and the sociological perspectives in detail I am left with only one conclusion and that is that human behaviour is not governed by the cognitive functioning domain, but human behavior is governed by the inner soul of man, which technically speaking means the Inner Interactive System of man. The main reason that we are not governed by our thinking is because each of us have the ability to choose, whatever we want unless we take away the ability to rationalize through different chemicals or drugs. Proof of this lies in the scientific facts that we all have unique finger prints, DNA, looks, hair, voices and†¦show more content†¦The illusive part of man is the way he thinks and behaves; this is most challenging to the sciences and thereby makes it totally impossible to create a social norm or a normal individual. Behavior and the expression thereof is totally different in every single individual. To be able to rationalize human behavior, we need to look at the holistic person; as every individuals finger print, DNA, looks etc are all different in every scenario. Behavior is therefore the illusive part of the psychological discipline as it is the psychologist who claim to be the experts in this field. I have found that many of them become both insulting and aggressive; when I pointed out the fact and proved to them that they are lacking the understanding of the word unique. If something is unique it is impossible to ever be normal. The whole psychological discipline is based on Social norms. Behavior can never be diagnosed as normal, however people could have numerous similarities and I think the impossibility of being normal is an embarrassment to the psychological fraternities doctrine, as science has proven the exact opposite. Although Psychology has marketed themselves under the medical sciences, their degree is not a science degree it is an arts degree. Behavior can never be a science as there are no starting points or ending point for it to be classified as a science; as

Epidemiology Of Childhood Obesity Health And Social Care Essay Free Essays

string(168) " utilizing the computing machine, and playing video games occupy a big per centum of kids ‘s leisure clip, which are act uponing their physical activity degrees\." This brings me to the Epidemiology of Childhood Obesity. One of the Major wellness jobs that plague the United States is Childhood fleshiness. Since the 1980 the sums of kids who have been considered fleshiness have been at an dismaying rise and the prevalence among kids under the age of 12 has more than doubled. We will write a custom essay sample on Epidemiology Of Childhood Obesity Health And Social Care Essay or any similar topic only for you Order Now â€Å" Harmonizing to the 1999-2002 National Health Association ( NHA ) study, 16 per centum of kids ages 6-19 old ages are overweight. The major population that seems to be plagued by childhood fleshiness are minority population. NHA found that African American and Mexican American striplings ages 12-19 were more likely to be overweight, A than non-Hispanic White adolescents.A The disparity of being overweight in the adolescences has been the major subscriber to a high hazard of developing high cholesterin, high blood pressure, respiratory complaints, orthopaedic jobs, depression and Type 2 Diabetes as a young person. One disease of peculiar concern is Type 2 Diabetes. Due to these addition in negative wellness behaviours The infirmary costs entirely associated with childhood fleshiness were estimated at $ 127 million during 1997-1999 ( in 2001 changeless U.S. dollars ) , up from $ 35 million during 1979-1981 † ( Department of Health and Human Services, 2010, p 1 ) The epidemiology triangle long-run effects of being an fleshy stripling is that there is a 70 % opportunity of them going overweight or corpulent grownups and 80 % if one or more parent in the place A is fleshy or corpulent. When fleshiness in childhood falls over into maturity, it increases the hazard of diabetes, high blood force per unit area, high cholesterin, asthma, arthritis, and a general hapless wellness position. In 2000, the entire cost of fleshiness for kids and grownups in the United States was estimated to be $ 117 billion where $ 61 billion are direct medical costs ( The World and I, 2006 ) . Childhood fleshiness has many finding factors.A The most outstanding factor that causes childhood fleshiness are A deficiency of physical activity, Unhealthy feeding, genetic sciences and societal factors, † socio-economic position, race/ethnicity, media and selling, and the physical environment are besides lending factors to child goon fleshiness. † ( Kumanyika, 2008 ) . In general, kids and striplings are eating more foodsA at fast nutrient eating houses than they are eating at place, imbibing more sugary drinks, and bite on more unhealthy nutrients like french friess and french friess often. This alteration is contributed to the American demand for Convenience. This is taking more people to devour speedy service or eating house repasts or to purchasing microwavable ready-to-eat, low cost, rapidly accessible repasts to fix at place. â€Å" The nutritionary composing of kids ‘s diets every bit good as the figure of Calories consumed is of involvement to find the consequence of nutrient ingestion on childhood fleshiness. In relation, part sizes increased between 1977 and 1996. Average part sizes increased for salty bites from 1.0 ounces to 1.6 ounces and for soft drinks from 12.2 ounces to 19.9 ounces. A Below shows the major alteration in nutrient parts, which has contributed to the major factors of fleshiness † ( Department of Health an d Human Services, 2010, p 1 ) A A A Figure 2: Proportion of Vegetable Helpings, 1999-2000 Figure 3: Proportion of Grain Servings, 1999-2000 Note: Children 2-19 old ages. Beginning: National Health and Nutrition Examination Survey, NCHS, CDC. Note: Children 2-19 old ages. Beginning: National Health and Nutrition Examination Survey, NCHS, CDC. A † Other surveies indicate that kids are non eating the recommended helpings of nutrients featured in the USDA nutrient pyramid and that there have been important alterations in the types of drinks that kids are devouring. i‚ ·A A A A A A A A Merely 21 per centum of immature people eat the recommended five or more helpings of fruits and veggies each twenty-four hours. As shown in figure 2, about half of all vegetable helpings are fried murphies. i‚ ·A A A A A A A A Percent entire energy from fat really decreased between 1965 and 1996 for kids, from 39 to 32 per centum for entire fat, and 15 to 12 per centum for concentrated fat. † i‚ ·A A A A A A A A In 1994-1996, adolescent misss and boys merely consumed 12 and 30 per centum, severally, of the Food Guide Pyramid ‘s helping recommendations for dairy ; and 18 and 14 per centum, severally, of the helping recommendations for fruit. † i‚ ·A A A A A A A A Soda ingestion increased radically in the early to mid-1990s. Thirty-two per centum of adolescent misss and 52 % of adolescent male childs consume three or more eight ounce helpings of soda per twenty-four hours. Soft drink ingestion for stripling male childs has about tripled, from seven to 22 ounces per twenty-four hours ( 1977-1978 to 1994 ) . Children every bit immature as seven months old are devouring sodium carbonate i‚ ·A A A A A A A A Milk ingestion has declined during the same period. In 1977-78, kids age 6-11 drank four times every bit much milk as any other drink. In 1994-1996 that decreased to 1.5 times every bit much milk as sugar sweetened drinks. In 1977-1978, striplings drank 1.5 times every bit much milk as any other drink and in 1996 they consumed twice every bit much sugar sweetened drinks as milk. Milk ingestion decreased for adolescent male childs and misss 37 and 30 % severally, between 1965, and 1996. † ( Department of Health and Human Services, 2010 ) . This research showsA thatA the lessening in existent physical activity and the addition in nutrient consumption is the major subscriber to childhood fleshiness. Physical activity tendency informations for kids are limited, but cross sectional informations indicates that one tierce of striplings are non having recommended degrees of centrist or vigorous activity, 10 % are wholly inactive, and physical activity degrees fall as stripling ‘s age ( Booth, Murphy, Phongsavan, Salmon A ; Timperio, 2007 ) . A A A A A A A A A Americans need for watching telecasting, utilizing the computing machine, and playing video games occupy a big per centum of kids ‘s leisure clip, which are act uponing their physical activity degrees. You read "Epidemiology Of Childhood Obesity Health And Social Care Essay" in category "Essay examples" â€Å" It is estimated that kids in the United States are passing 25 % of their waking hours watching telecasting and statistically, kids who watch the most hours of telecasting have the highest incidence of fleshiness ( Department of Health and Human Services, 2010, p1 ) . This tendency is evident and a major hazard factor to child goon fleshiness because while the sedentary activity of watching Television and picture games normally involves the composing of repasts high in fat. Along with the dietetic alterations that affects child goon fleshiness schools are besides lending to the job by diminishing the sum of free drama or physical activity that kids receive during school hours. There are merely a 3rd of American simple schools, allow kids to hold day-to-day physical instruction, and merely a 5th of the simple schools have extracurricular actives for the kids to take part in. â€Å" Daily registration in physical instruction categories among high school pupils decreased from 42 % in 1991 to 25 % in 1995, later increasing somewhat to 28 % in 2003 † ( Department of Health and Human Services, 2010, p 1 ) . â€Å" Experts have looked progressively to the physical environment as a driver in the rapid addition of fleshiness in the United States. In urban countries, infinite for out-of-door diversion can be scarce, forestalling kids from possessing a protected topographic point to play. Neighborhood offense, unattended Canis familiariss, or deficiency of street lighting may besides suppress kids from being able to walk safely out-of-doorss ; and busy traffic can hinder commuters from walking or bicycling to work as a agency of day-to-day exercising. Though few surveies are available on the direct effects of the physical environment on physical activity, there are marks of the possible for betterment, evidenced by Toronto ‘s 23 % addition in bike usage after the add-on of motorcycle lanes, and London ‘s pathway usage addition within the scope of 34-101 % ( depending on location ) as a consequence of improved lighting there has been less research on the relationship between the physical environment and physical activity for kids than for grownups ; nevertheless the findings for kids appear to be consistent with those of the grownup population. The per centum of trips to school that kids walked declined from 20 % in 1977 to 12 % in 2001. Because kids spend a significant sum of clip going to and from school, this may be an country in which to integrate and increase physical activity into kids ‘s day-to-day wonts † ( Department of Health and Human Services, 2010, p 1 ) Surveies suggest that parental nutrient penchants straight influence and form those of their kids. In a survey by Oliveria and co-workers, they reported that parents who ate diets high in concentrated fats besides had kids who ate diets high in concentrated fats ( Birch A ; Fisher, 1998 ) . â€Å" It is suspected that this observation is non simply due to the nutrients parents feed their kids, but instead due to the penchants kids develop through exposure to nutrients that their parents take to eat in their lives. Birch and Fisher postulate that exposure to fruits and veggies and nutrients high in energy, sugar and fat may play an of import function in set uping a hierarchy of nutrient penchants and choice in childs. Other surveies have showed that when parents eat fruits and veggies and they are readily available the penchants for kids to wantA such an point as a pick of bite are increased † ( Department of Health and Human Services, 2010, p1 ) Research workers besides indicate that the societal context in which a kid is introduced to or has experiences with nutrient is instrumental in determining nutrient penchants the feeding environment that a kid is involved in will find the feeding pattern the kid will do in his or her life-time ( Birch, 2006 ) . â€Å" For many kids, feeding is a societal event that frequently times occurs in the presence of parents, other grownups, older siblings and equals. Children typically observe the behaviours and penchants of others in their milieus. This becomes the function theoretical accounts. Children observation in unhealthy eating wonts and behaviours have brought a rise in childhood weight jobs † ( Department of Health and Human Services, 2010, p1 ) . â€Å" Several possible mechanisms have been proposed to explicate this phenomenon including the followers: i‚ ·A A A A A A A A Constraints on parent ‘s clip potentially contribute to kids ‘s weight jobs, as working parents likely rely more to a great extent than non-working parents on prepared, processed, and fast nutrients, which by and large have high Calorie, high fat, and low nutritionary content. i‚ ·A A A A A A A A Children left unsupervised after school may do hapless nutritionary picks and prosecute in more sedentary activities. i‚ ·A A A A A A A A Childcare suppliers may non offer as many chances for physical activity and may offer less alimentary nutrient options. i‚ ·A A A A A A A A Unsupervised kids may pass a great trade of clip indoors, possibly because of safety concerns, watching Television or playing video games instead than prosecuting in more active out-of-door chases. â€Å" ( Department of Health and Human Services, 2010 ) . In short, the recent societal and economic alterations in American society have encouraged unhealthy wonts of extra ingestion. â€Å" These alterations have [ influenced ] the nutrients available in the places, the grade of influence parents have when kids make nutrient choices and has led to additions in sedentary behaviours among young person † ( Department of Health and Human Services, 2010, p1 ) A Finally there has been a big argument over whether or non overexposure to nutrient advertisement has increased the incidence rates of childhood fleshiness. Although there has been a positive correlativity between â€Å" the hours of telecasting viewed, organic structure mass index, and fleshiness incidence has been documented, the exact mechanisms through which this occurs are still being investigated. It has been estimated that the mean kid presently views more than 40,000 commercials on telecasting each twelvemonth, a crisp addition from 20,000 in the seventiess † ( Department of Health and Human Services, 2010, p1 ) . Furthermore, an â€Å" accrued organic structure of research reveals that more than 50 per centum of telecasting advertizements directed at kids promote nutrients and drinks such as confect, convenience nutrients, bite nutrients, sugar sweetened drinks and sweetened breakfast cereals that are high in Calories and fat and low in fibre and alimentary densenes s. The statistics on nutrient advertisement to kids indicate that: i‚ ·A A A A A A A A Annual gross revenues of nutrients and drinks to immature consumers exceeded $ 27 billion in 2002. i‚ ·A A A A A A A A Food and drink advertizers jointly spend $ 10 to $ 12 billion yearly to make kids and young person: more than $ 1 billion is spent on media publicizing to kids ( chiefly on telecasting ) ; more than $ 4.5 billion is spent on youth-targeted public dealingss ; and $ 3 billion is spent on packaging designed for kids. i‚ ·A A A A A A A A Fast nutrient mercantile establishments spend $ 3 billion in telecasting ads targeted to kids † ( Department of Health and Human Services, 2010, p1 ) . Available research shows that there are a figure of root causes of fleshiness in kids. Choosing one or two chief causes or indispensable factors is following to impossible given the current information because the possible influences of fleshiness have many interlacing factors. There are big spreads in cognition and research, which is restricting the ability to nail a peculiar cause and find the most effectual ways to battle childhood obesity. â€Å" Another research spread stems from deficiency of a perspective longitudinal survey that links dietetic and other behaviour forms to development of fleshiness. Another complication of current informations is that there is a demand for more precise and dependable steps of dietetic consumption and activity degrees, as single callback of events and diet are non the most reliable beginnings for information † ( Department of Health and Human Services, 2010, p1 ) . When believing approximately early bar of fleshiness, it is indispensable that more is understood about how genetic sciences is involved and how the cistrons are triggered or respond to environmental alterations and stimulation. â€Å" Research is merely get downing to explicate how gustatory sensation penchants develop, their biochemical underpinnings and how this information may be utile in controling childhood weight addition † ( Department of Health and Human Services, 2010, p 1 ) . Primary bar is non an option for many kids who are already fleshy. Research on successful intercessions for kids who are fleshy or at hazard of going corpulence is highly of import to cut down efficaciously childhood fleshiness in this state ( Maternal and Child Health Library, 2008 ) . Generally, research has merely begun to rub the surface in clarifying the causes of fleshiness in kids. Filling in the cognition spread will take clip, as implementing some of the survey designs that will outdo light the complex interactions are clip devouring and dearly-won. However, the basicss are clear, to remain healthy, eat a balanced diet and give equal clip to physical activity ( Department of Health and Human Services, 2010 ) . This will assist epidemiologists and maintain down the cost of going healthy. How to cite Epidemiology Of Childhood Obesity Health And Social Care Essay, Essay examples

Beazer Homes Case free essay sample

Investors were lead to believe that the company financials were healthier than they actually were, as evidenced by the changes noted when the financial statements had to be restated. As a result of doing this, investors who were under the impression of a healthier position, continued to invest in an organization that was essentially doing nothing more than stealing their money; money which could have been invested into a different enterprise rather than padding the pockets of executives that didnt earn it. As a result of having to restate financial statements, the per share price of Beazer Homes dropped from the $35/share price level in may, to approximately $11/share by the end of July. This is a significant loss in wealth for investors. In addition to the allegations against Mr. Rand for possible accounting fraud, allegations were also brought against Beazer Homes for mortgage fraud. To address the question as to which is a more serious offense, it would be our opinion that both would carry an equal weight of seriousness. We will write a custom essay sample on Beazer Homes Case or any similar topic specifically for you Do Not WasteYour Time HIRE WRITER Only 13.90 / page On the one hand, investors were misled, as noted above, and this led to a significant loss of wealth for many, especially those individuals and/or institutions that may have held a large position. On the other hand, to address the issue of mortgage fraud, new homeowners were oftentimes cheated out of money that they paid to Beazer Homes. A example of this is when Beazer Homes would require purchasers to pay a fee for interest discount points at closing. Then Beazer Homes would keep the cash received and not lower the interest rate. This is just one example, but it can be an extremely costly one when you look at how much a . 25 percent or . 5 percent reduction in an interest rate can be over the life of a 20 or 30 year fixed rate mortgage; thats if Beazer Homes wasnt trying to convince people that an adjustable rate or hybrid mortgage would be better for their situation. Additionally, Beazer Homes ignored income requirements when making loans to unqualified purchasers, which not only put the purchaser in jeopardy of having the income needed to make their ayments, but in the event of default or foreclosure, it can have a significant impact on the home values of the neighborhood. As a result of these legal issues with Beazer Homes, the SEC issued a notice to the Beazer Homes CEO called the Wells notice. The Wells notice was created under the Sarbanes-Oxley Act of 2002, which states that if a firm has to restate their financial statements, the SEC can require the CEO and CFO to return any and all bonuses that were received during the period of restated financial statements. Additionally, the CEO and CFO do not need to have any knowledge of errors. The SEC issued the Wells notice to the Beazer Homes CEO, Ian J. McCarthy, on 13 November 2009, indicating that the SEC would be brining a civil case against him to collect incentive compensation. In the notice issued to the CEO, there was no indication or allegations of cover-up, or misconduct, on the part of Mr. McCarthy with respect to the financial statements or other disclosures that were published during the period in question.

Erosion and Deposition

3 Easy Ways to Supplement Your Freelance Writing Income

3 Easy Ways to Supplement Your Freelance Writing Income All it takes is a willingness to do some writing projects that may not be particularly well-paying, exciting or creative, but can bring in enough extra dollars to keep you going between projects. Outlined below are three ways you can explore temporary and one-time jobs. Utilize Craigslist in Multiple Cities Search for one-time writing gigs on Craigslist, and search for jobs in cities outside of your geographical area. Here is a simple way to bookmark the classified pages for jobs listed in any city, using the city of Chicago as an example: 1) Type Chicago craigslist in your browser bar2) Click on Classifieds: Jobs. Bookmark the page (I have 22 major cities bookmarked.)3) Scroll down the â€Å"jobs† category and click on â€Å"writing/editing.† If you don’t find anything of interest, go back to the jobs page, scroll to the bottom of the category listing and click on â€Å"Gigs.  Ã‚     Craigslist is free; try posting your services under â€Å"Resume† and troll for jobs in major cities.   Create an Account at Amazon Mechanical Turk Sign up to be a â€Å"turker† on the Mechanical Turk Welcome Page. This division of Amazon.com employs people to do a variety of tasks, including writing, for hundreds of clients. The easiest way to learn the ropes, get advice and learn shortcuts is to join Turker Nation. This free forum provides great tips about which writing and editing tasks to choose. The downside to turking is that you forfeit all copyrights to what you have written. However, most writing tasks involve nothing more than a few paragraphs describing a place or a product. You choose to get paid via PayPal or an Amazon.com gift card. The other appealing aspect of turking is that there are a variety of non-writing tasks you can do- some can even be done while you watch television. I sometimes take several short surveys a day, and Collect brochures, business cards, fliers and marketing materials from local businesses. Review the documents. Note editing suggestions, or rewrite any text that is grammatically incorrect or just plain clunky. (Don’t edit or rewrite the entire piece; do just enough to illustrate how a professional touch can make a difference.) Go to the business owner and present your ideas; suggest that you would be willing to edit or rewrite portions that would help them advertise their business more profitably, or that would help present their business to the public in a more professional light. Be willing to do the work for less than your normal fee. Many small business owners don’t have polished advertising materials because they couldn’t afford it in the first place. Ask that your services be recommended to other local businesses.

Natural Selection Lab Report Example | Topics and Well Written Essays - 500 words

Natural Selection - Lab Report Example eby the trait of interest has an optimum value, and finally, Disruptive curve in which organisms that have the largest and the smallest values of any given trait boots of highest fitness value and conversely, organism that have intermediate values are disadvantaged. Considering the above stated facts, it is seen that in the long term, Directional selection results to generation of the new type of species from the existing species. This is unlike stabilizing in which the given specie maintains its existing type without any variation over the long period of time. It has been found that stabilizing selection results in the refinement of the existing specie type. On the other hand, disruptive selection facilitates favouritisms of given individuals of a given phenotype (Williams). This experiment’s main objective is the comparison on how the population size varies in different generations depending on different environmental conditions, determination of the effect of different predator types on the population of prey, and the gaining of graphing and interpretation knowledge. In this habitat, the number of Clothespin is increasing linearly while knives and spoons are decreasing as the generation changes. However, number of spoons decreases from first generation to second generation, then it starts increasing. In this habitat, the number of S. pea preys decreases tremendously in all the generation. The number of White and pinto decreases from first generation to second generation and starts increasing from generation 2 to generation 3 The number of Forks and clothespin in this habitat is almost constant. The change in the number of spoons increases tremendously from generation 1 to generation 2 and decreases from generation 2 to generation 3 As the Number of predators increases, the number of preys decreases. This is due to the fact that an increase in the number of predators results into more preys being eaten and as a result, their (prey) number decreases. Also,

Marketing ethics Essay Example | Topics and Well Written Essays - 3000 words

Marketing ethics - Essay Example However, in contemporary competitive market, the task of aligning is excessively challenging (Appelbaum, et al., 2009). In this particular study, the researcher will primarily focus on ethics of marketing, which addresses certain standards and principles associated with suitable conduct in the market (Ferrell, n.d.). According to the author, marketing is an activity usually conducted by an organization to promote a particular product or service and unethical practices arise out of pressure to achieve performance objectives. Misleading sales approach, overbilling customers, price fixing and fraud antitrust are all categorized as unethical marketing practices. Although such practices may fetch short-term benefits for the company; in the long run, these have devastating impacts. Such impacts may deteriorate financial performance of a company or tarnish its reputation to such an extent that downfall of the company becomes inevitable. This is precisely the reason why conducting ethical marketing is so important. Organizations that efficiently manage ethics are able to methodically absorb, respond and adap t to most breakdowns in decisions or conduct. In the contemporary consumer oriented society, human rights play a crucial role. Given the aforesaid fact, greater number of companies has been exposed to several positive as well as negative ethical issues of which count of the latter is increasing day by day. This has been largely possible due to rising power of media and the way this system is structured. Consequently, the system has a considerable impact on organizations that are involved in such means. In light of the aforementioned facts, this study will take a look at GlaxoSmithKline, which is a UK based pharmaceutical company and assess few of the ethical marketing challenges faced by the company, thereby seeking evidences as to why these

The European Occupation of the Middle East Literature review

The European Occupation of the Middle East - Literature review Example The problems which had begun with the European occupation continued to increase after independence to such an extent that they led to the Arab Spring between 2011 and 2012. Despite the fact that these countries were given independence, the western powers have continued to exert their influence on the region to such an extent that they have come to inspire the hostility of the Middle Eastern population. During the European occupation of the Middle East, the population in the occupied territories was denied any political freedoms. They could not directly elect their representatives, and where they were allowed to do so, these representatives did not have enough power to effectively represent their people. Many in the Middle East, therefore, agitated for the independence of their countries in order to regain the political freedoms that they had lost. They felt that it was their right to have self-determination, and not have their future decided for them by the European colonial powers. When the occupied territories in the Middle East were finally given independence, there was a high expectation among the populace that it was the start of a new age of freedoms (Cleveland 2010, p.408). This, however, turned out not to be the case because the governments which came to power tended to be autocratic which worked towards further denying their people their basic freedoms so that they could remain in power. The failure to deliver on their promises at independence led to their lack of legitimacy among the populace and the only way that they could legitimately remain in power was through the use of force. The vast oil reserves that were discovered in the Middle Eastern countries were used by these regimes to gain the necessary financial power to retain their authority (Cleveland 2010, p.514). It is the lack of political freedom in their countries which led the populations of various Middle Eastern nations to recently stage demonstrations against their governments, and it is these demonstrations, and at times military conflict, which came to be termed as the Arab Spring. One of the means through which the European powers established their dominance in the region was the favoring of the Christian population over the Muslim one. Since the European powers were Christian, they chose to strengthen the influence of their fellow Christians in the Middle East as well as to protect them from what they perceived to be a threat from the Muslim population.

Limiting Factors in a Business Situation

Limiting Factors in a Business Situation (a) Explain what a limiting factor is and what sort of things can become limiting factors in a business situation? (16 marks) Limiting factor is any factor that restricts a company or an organisations activities. In other words, limiting factor is a factor which is limited or not enough provide to the company. Limiting factors in an organisation can be labour hours, raw material, machine hours or space. For example, when sales demand excess the productivity capacity, the company do not have enough resources to produce the products, the scarce resource will be the factor that restricts the companys activities. Hence, the scarce resources should be identified to ensure company has enough resources to produce their products as many as their wish. By using limiting factor, we can maximise the profit when obtained the greatest possible contribution to profit each time. Example1: A B C Contribution per unit of output RM 24 RM 20 RM 12 Machine hours required per unit of output 6 hours 2 hours 1 hours Estimated sales demand 3,000 units 3,000 units 3,000 units Required machine hours 18,000 hours 6,000 hours 3,000 hours The machine hour is limited to 18,000 hours for the period because of the breakdown of one machine. Consider Example 1. From the example 1, we know that the company required total 27,000 machine hours to produce the total sales demand of the product A, B and C that they estimated. However, the company only has 18,000 machine hours for the period because of the breakdown of one machine. In this situation, companys activities are limited by the machine hours. When we looking at the above information, we will think that the company should produce the product A first since the contribution per unit of product A is the highest, but this could be wrong. This is because produce each unit of product A required 6 machine hours, but product B required 2 machine hours and product C required 1 machine hours only. So, the company can produce 3,000 units of product B and C respectively first, after that just produce the product A with the remaining machine hours. In other words, if the company concentrates on produce the product A, there will no machine hours left to the company to produce B and C. In order to maxi mize the companys profit, we should use limiting factor to calculate the greatest possible contribution per profit for each product and rank the profitability of the product to obtain the optimum production plan. (b) Explain the techniques that have been developed to assist in business decision- making when single or multiple limiting factors are encountered (16 marks) Single limiting factor- Limiting factor analysis When single limiting factor are encountered, we have to use limiting factor analysis to help companies to identify the scarce resources and maximise profit by using the best combination of available resources. In limiting factor analysis, we should identify the bottleneck resources first. Secondly, we should calculate the contribution per unit for each product. Next, we can calculate the contribution per unit of the bottleneck resource for each product after we get the contribution per unit of each product. After this, we can rank the products from the highest to the lowest in sequence based on contribution per unit of bottleneck resource. Finally, we can allocate the resources from the highest contribution per profit to the lowest contribution per profit by the ranking until the resources are used up. By doing so, we can obtained the greatest possible profit when resources are limited by single limiting factor. Example 2: X Y Machine hours per units 3 hours 4 hours Sales demand 2,000 units 3000 units RM RM Selling price 32 50 Less : Direct Material 10 20 Direct Labour 5 8 Variable Overhead 5 8 20 36 Contribution 12 14 The supply of materials for the period is unlimited, but the machine hours are limited to 15,000 hours. In order to maximize the profit, we should using limiting factor analysis to solve the problem when there is only one limiting factor. Step 1: Identify the bottleneck resource. At sales demand level: Sales demand Machine hours per unit Total machine hours X 2,000 units 3 hours 6,000 hours Y 3,000 units 4 hours 12,000 hours 18,000 hours Thus, machine hours are the limiting factor. Step 2: Calculate the contribution per unit for each product. The contribution has been given at the above. X Y Contribution per unit RM 12 RM 14 Step 3: Calculate the contribution per unit of the bottleneck resource for each product. To calculate the contribution per unit of the bottleneck resource for each product, the formulae is: Contribution per units of the machine hours = Contribution Machine hours Product X = RM 12 3 hours = RM 4.00 Product Y = RM 14 4 hours = RM 3.50 Step 4: Rank the products from the highest contribution per machine hour to lowest contribution per machine hour. Production should be concentrated on product X first, up to maximum sales available, then product Y. Step 5: Finally, allocate the available resources using that ranking that we decided at step 4 and calculate the maximum contribution. Production plan Units produced Machine hours per unit Total machine hours Balance of machine hours 15,000 hours Product X 2,000 units 3 hours 6,000 hours 9,000 hours Product Y 2,250 units 4 hours 9,000 hours So, the maximum contribution is as follows: RM Product X ( 2,000 units x RM 12) 24,000 Product Y (2,250 units x RM 14) 31,500 55,500 Multiple limiting factors- Linear programming We can use limiting factor analysis when there is one limiting factor. However, when there is more than one of scare resources which restricts organisations activities, we can use linear programming to solve the problem. Firstly, we must define the variances when using linear programming. Then, we can define and formulate the objective. After formulate the objective, we also must formulate the constraints. Next, draw a graph to identify the feasible region and get the optimum production plan from the graph. Finally, we can solve the problem and get the maximum contribution by doing so. Example 3: A B Contribution per unit RM 20 RM 10 Machine hours per unit 6 hours 3 hours Kilos per unit 4 kilos 8 kilos Maximum available : Machine hours = 18,000 hours Kilos = 24,000 kilos What should be the production plan? To answer the example 3, we should use linear programming to get the optimum production plan because there is two or more of scarce resources. Step 1: Define the variances Let x = the number of units of the product A. y = the number of units of the product B. Step 2: Define and formulate the objective function. The objective is to maximize the contribution C, given by: Maximum contribution = 20 x + 10 y Step 3: Formulate the constraints. The limitations here are machine hours and kilos. For the machine hours, product A required 6 hours and product B required 3 hours machine hours. So, total machine hours required = 6 x + 3 y For the kilos, product A required 4 kilos and product B required 8 kilos. So, total kilos required = 4 x + 8 y Constraints Utilised Available Machine hours 6 x + 3 y 18,000 Kilos 4 x + 8 y 24,000 Step 4: Draw a graph and identify a feasible region. For the equation 6 x + 3 y = 18,000 machine hours When x = 0, y = 18,000/ 3 = 6,000 When y = 0, x = 18,000/ 6 = 3,000 Draw a straight line between the point (0, 6000) and (3000, 0) on the graph to represent the line for machine hours constraint. For the equation 4 x + 8 y = 24,000 kilos When x = 0, y = 24,000/ 8 = 3,000 When y = 0, x = 24,000/ 4 = 6,000 Draw a straight line between the point (0, 3000) and (6000, 0) on the graph to represent the line for kilos constraint. The graph is shown as below: The original constraints were Step 5: Determine the optimal solution Calculate the total contribution at each point P, Q and R Point P = RM 20 (0) + RM 10 (3,000) = RM 30,000 Point Q = RM 20 (2,000) + RM10 (2,000) = RM 60,000 Point R = RM 20 (1,500) + RM10 (0) = RM 30,000 Point Q gives the maximum contribution. Step 6: Answer the question The optimal point is at x = 2,000 and y = 2,000. This gives a maximum contribution of C = (20 x 2,000) + (10 x 2,000) = RM60, 000 (c) Explain the management idea known as throughput accounting. State and justify your opinion on whether or not throughput accounting and limiting factors are the same thing. (18 marks) For every company to reduce it costs and improve the profitability of the company, managers will use cost accounting to help them on decision-making. Hence, Theory of constraints (TOC) or Throughput accounting (TA) is another method for decision-making apart from Standard Based Costing, Activity Based Costing and Marginal Costing. TOC/TA is a new management accounting approach based on factors identification when the constraints are restricts companies to achieving their goals and reduces companys profits. Throughput accounting is used when there are few constraints only, usually just one. The constraint can be a resource, company policy or management mindset. According to Goldratts ideas, TOC is forecasting on a limit capacity at certain critical points in any production plan. Therefore, TOC maximise organisations profit by increasing the producing speed through an organisation in order to eliminating bottlenecks. Additionally, throughput accounting is not costing because it does not include variable and fixed expenses, and overheads to products. Thus, throughput accounting helps managers to get better management decision in order to improve organisations profits by three measurements. They are: Throughput (T) is the rate of money that a company produced, throughput is total sales (S) less total variable costs (TVC), usually is cost of raw materials ( T = S TVC ). However, T exists even there is only one product are sold. Besides, finished goods of inventory in a warehouse that not yet sold are not included. Investment (I) is total amount of money that invest in a new system to enhance its ability to improve the capacity, for examples machinery. Operating expenses (OE) is all others expenses except the total variables cost when calculate the throughput. Basically, OE is total costs to operating the production system, for examples maintenance, utilities, rental, etc. Fixed or partially fixed costs are no difference in throughput accounting. On the contrary, there have either total variable cost or operating expenses in throughput accounting. Therefore, throughput accounting use difference formulas to make difference types of accounting decisions by combined the throughput, total variable costs and operating expenses: Net profitÂÂ  (NP) = Throughput Operating Expense = T-OE Return on investmentÂÂ  (ROI) = Net profit / Investment = NP/I ProductivityÂÂ  (P) = Throughput / Operating expense = T/OE Investment turnsÂÂ  (IT) = Throughput / Investment = T/I According to Dr. Goldratt, we can use the above formulas to get the right decision when making a decision that related to changes in revenue, expenses or investments, which must get a positive answer from one out of three questions below: Does it increase throughput? Does it reduce operating expense? Does it improve the return on investment? Finally, there are five steps established by Goldratts in the TOC to help managers maximize the throughput and then achieve organisations goals. The five steps are as follows: Identify the system constraints. There is either an internal constraint (in production, engineering or planning.) or an external constraint (in the market)? The constraint is a resource or a policy? Decide how to maximise the output from the constraint. All other activities are prepared subject to this decision. Non-constraints must be subject to constraints. Consider the appropriate level of resources once the resource constraint has been identified. Therefore, the capacity constraints can be improved. Enhance the systems constraints. Once constraint has been corrected, return to Step 1 to determine the next most serious constraints and duplicate the above steps. In my opinion, throughput accounting and limiting factor is not the same thing but there are similarities and differences in between throughput accounting and limiting factor. For example, throughput accounting and limiting factor are using to assist companies identify bottleneck resources instead to maximise companies profits. However, throughput accounting is used when there are few constraints; normally just one but limiting factor is used when there are one or more than one constraints. Besides, limiting factor is focus on working to obtain greatest contributions while throughput accounting is focus on some critical areas that have limited capacity at any production plan. In addition, limiting factor maximise the organisations profit by using the best combination of available resources but throughput accounting is maximise the profit by increase the producing speed through organisation to eliminate bottlenecks. Throughput accounting calculates the products throughput as sales price minus total variable costs. Variable costs or in other words cost of materials in throughout accounting included direct material costs only, labour and overhead costs are fixed and categories to total factory costs. In contrast, limiting factor calculates contribution as sales price minus variable costs but labour and overhead costs are part of variable costs in limiting factor, this is difference from throughput accounting.

Utilitarianism Essay -- Ethical Issues, Physician Assisted Suicide

The United States flag stands to the world as a signal of freedom and most importantly choice. The constitution gives our citizens that right to choose how to live life, how to use our liberty, and how to pursue our own happiness. But what happens when a citizen decides to opt for no life? Is that not a choice? This is the argument for one of the most controversial questions of the past decade, should assisted suicide be deemed legal in the United States? The root of the controversy is the involvement of medical community in such a choice. I will look to find a not an answer but guidance to determine if assisted suicide is an ethical choice. While the issue has no answer that would make both sides of the issue content, Utillitarism and relative ethics can help clear the ethical issue at hand. The utillatirist perspective will help explain how the outcome of physician assisted suicide helps a population with a certain end benefits and changes the quality of life of a person who is on a tight schedule to meet a certain death. Relativism will explain how the circumstances that the human being that benefit from assisted suicide call for a dignified ending. Utilitarianism will have us look at the outcome of an action as the guiding principle to deem something ethical or unethical (Moser, 2010). The outcome of actions is in a sense the harm or benefit that will remain after it is all said and done. Realistically we cannot expect to find an answer to the question of ethics pertaining to physician assisted suicide. Perhaps the most important aspect to understand about physician assisted suicide is that this choice is guided not to the common person that has just gone through a rough patch and cannot see the end. This choice is directed... ...he legalization of physician assisted suicide. Not to ignore the wishes of the medical community, we must focus on the wishes of the patient. Again physician assisted suicide is not a way out of a bad situation is a way to approach the inevitable. It is to be held relative to the individual’s personal wishes and medical history and prognosis. No one situation is the same and every single patient needs to be treated accordingly to their own situation. There is not simple answer to this, but we must move forward to help the majority in a dignified way relative to their own special situation. Imagine a fragile person whose color has turned an ash white, hair gone, constantly sick to their stomach, unable to do the most simple of task like hugging their loved ones. How can a heart condemn a human being for wanting to be remembered as more than that in their last days? Utilitarianism Essay -- Ethical Issues, Physician Assisted Suicide The United States flag stands to the world as a signal of freedom and most importantly choice. The constitution gives our citizens that right to choose how to live life, how to use our liberty, and how to pursue our own happiness. But what happens when a citizen decides to opt for no life? Is that not a choice? This is the argument for one of the most controversial questions of the past decade, should assisted suicide be deemed legal in the United States? The root of the controversy is the involvement of medical community in such a choice. I will look to find a not an answer but guidance to determine if assisted suicide is an ethical choice. While the issue has no answer that would make both sides of the issue content, Utillitarism and relative ethics can help clear the ethical issue at hand. The utillatirist perspective will help explain how the outcome of physician assisted suicide helps a population with a certain end benefits and changes the quality of life of a person who is on a tight schedule to meet a certain death. Relativism will explain how the circumstances that the human being that benefit from assisted suicide call for a dignified ending. Utilitarianism will have us look at the outcome of an action as the guiding principle to deem something ethical or unethical (Moser, 2010). The outcome of actions is in a sense the harm or benefit that will remain after it is all said and done. Realistically we cannot expect to find an answer to the question of ethics pertaining to physician assisted suicide. Perhaps the most important aspect to understand about physician assisted suicide is that this choice is guided not to the common person that has just gone through a rough patch and cannot see the end. This choice is directed... ...he legalization of physician assisted suicide. Not to ignore the wishes of the medical community, we must focus on the wishes of the patient. Again physician assisted suicide is not a way out of a bad situation is a way to approach the inevitable. It is to be held relative to the individual’s personal wishes and medical history and prognosis. No one situation is the same and every single patient needs to be treated accordingly to their own situation. There is not simple answer to this, but we must move forward to help the majority in a dignified way relative to their own special situation. Imagine a fragile person whose color has turned an ash white, hair gone, constantly sick to their stomach, unable to do the most simple of task like hugging their loved ones. How can a heart condemn a human being for wanting to be remembered as more than that in their last days?

Negotiating Skills

Negotiation refers to the process of reaching an agreement that is acceptable to all parties. Thus, it necessarily requires the recognition and analysis of the interests of all parties. Successful negotiation requires careful understanding of the perceptions and interests of each party and the utilization of surefire techniques of negotiation (Management Sciences for Health and United Nations Children’s Fund 1998). It is suggested by many that the hardest part in any negotiation occurs before the parties sit down at the negotiation table. This means that a lot of the success in negotiation may be attributed to adequate preparation prior to the actual negotiation process itself (Management Sciences for Health and United Nations Children’s Fund 1998). Preparation to negotiation involves planning and intelligence gathering. One of the important things that a negotiator must learn include the interests and expectations of the parties, the non negotiable and negotiable terms, different negotiation strategies, and possible concessions and other alternatives. Preparing adequately for negotiation would enable the negotiator to anticipate issues and problems and plan strategies in advance, placing him at an advantage (Dolan 2004). Negotiators must act ethically in any given situation. It should be kept in mind that the goal of negotiation is the resolution of conflict and reaching an agreement mutually acceptable to parties. Therefore, both parties must treat each other with respect, transparency and honesty so that the process remains a viable option in case of conflicts of interest (Cohen 2004). Finally, negotiators must know how to act when actions get stalled. There may be no hard and fast rules in such kinds of situations; the ultimate guide to any negotiator lies in the nature of the negotiation process itself, which is a tool for reaching an agreement. Thus, when actions get stalled, parties must exert effort to choose alternative courses of action that could still benefit all stakeholders (Management Sciences for Health and United Nations Children’s Fund 1998). References Cohen, S. P. 2004, â€Å"Negotiation Ethics: A Matter of Common Sense.† The   Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚   Negotiator Magazine [Online], Available at    http://www.negotiatormagazine.com/article217_1.html Dolan, J. P. 2004, ‘Six Steps For Negotiation Preparation,’ Available at Management Sciences for Health and United Nations Children’s Fund. 1998, ‘Negotiation Techniques,’ Available at http://erc.msh.org/quality/ittools/itnegot2.cfm

Greek Philosophy Essay

What Is Philosophy? †¢Philosophy : The studies of Greco-Roman thinkers on activities and inquiries. It is also the rational investigation of the truths and principles of being, knowledge, or conduct. †¢Philosophy focuses on three main types: †¢Stoicism †¢Skepticism †¢Epicurean †¢Philosophy consists of these philosophical areas: †¢Metaphysics †¢Materialism †¢Idealism †¢Epistemology †¢Empiricism †¢Rationalism †¢Ethics †¢Hedonism †¢Cynicism Three Main Types Stoicism †¢Refers to the knowledge of Aristotle o†Mind is a blank state, impressions are made by the 5 senses. † †¢Stoics deny the metaphysical points of view. oReal objects produce intense feelings. oThe body and soul are pairs that act and react to each other. Skepticism †¢Examines as to what someone should believe- derived from Plato’s schooling †¢Objections on skepticism: oIts commitment to knowledgeable limitation is nonexistent. oIf knowledge is limited and judgment is not expressed, life is presumed unlivable. Epicurean †¢Formulated by Epicurus who believed philosophy was studied to make the soul happy. †¢Happiness created with less wanting of materialistic things and more peace. Philosophical Areas Metaphysics †¢Branch of philosophy accountable for the study of existence. oAnswers â€Å"what is? † †¢The foundation of philosophy oWithout metaphysics, we would not be able to comprehend the world or act accordingly to it. Materialism †¢Refers to the simple focus of the material world. o†Everything in the universe is matter and matters. † †¢The philosophy is held by those who believed that material items are accountable for existence. Idealism †¢Stresses the central ideal and spiritual interpretations of experiences. oThey believe world exists as a spirit †¢Two forms: oMetaphysical idealism oEpistemological idealism Epistemology †¢The investigation of grounds and nature of knowledge of the world. oFocuses on the knowledge of differences between truths and falsehood. †¢Fundamental aspect to how we think. Empiricism †¢Theory of experience as primary source to our knowledge of the world. oLearning through perception. †¢Classical empiricism oRejection of innate, in-born knowledge and concepts †¢Radical empiricism oExplains that all our knowledge is derived from our senses. †¢Moderate empiricism oDescribes the exceptions to general empiristic rules. Rationalism †¢Philosophical movement that introduced mathematical methods to philosophy. oCan be understood through mathematical and logical  principles, not sensory experiences. Ethics †¢Branch of philosophy dealing with what is the proper action for humans. oAnswers â€Å"What do I do? † †¢Requirement for human life, decides course of action. Hedonism †¢Doctrine that states that all pleasure is naturally acceptable- good for the soul. †¢Nothing but pleasure is good. Cynicism †¢Described as a way of life, which consists of asceticism, anti-conformism, and anti-conventionalism. †¢Basis of cynicism is the virtue of well being and a happy life. Philosophers Socrates †¢Possibly the wisest sage of all time †¢Contributions to philosophy: oPithy sayings. oSocratic method of discussion o†Socratic† irony oSocratic method- saying he knows nothing and that unexamined life is not worth living †¢Participated in the military during the Peloponnesian War. oCommitted suicide by ingesting poison hemlock. Plato Fun fact: Plato is not his original name- it’s Aristocles, but was later changed to Plato by his teachers †¢Considered the most important philosopher to have ever lived- father of Idealism. †¢Thought the human soul contained reason, spirit, and appetite. †¢Student and follower of Socrates. †¢Impacted math, science, morals, and political theories with his  Legacy of the Academy schooling. Aristotle †¢Student of Plato, teacher of Alexander the Great. †¢Wrote on logic, nature, psychology, ethics, politics, and art. †¢Developed deductive reasoning. †¢Basis: Aristotle’s syllogism †¢Church used Aristotle to explain doctrines in the Middle Ages. Concept of â€Å"Prime Element † †¢Thales – Attempted to find naturalistic explanations of the world; identified â€Å"water† as the ultimate principle. †¢Pythagoras – Creator of Pythagorean Theorem; believed â€Å"earth† was what encompassed all beings. †¢Anaximenes – Explained how â€Å"air† was universally present and is the source of all that exists. †¢Heraclitus – Disagreed with aforementioned philosophers and claimed â€Å"fire† was the classical element. †¢Empedocles – Created the cosmogenic theory that composed of the four classical elements: water, earth, fire, and air. Bibliography †¢http://www. philosophybasics. com/movements_rationalism. html †¢http://www. importanceofphilosophy. com/Ethics_Main. html †¢http://philosophy. lander. edu/ethics/hedonism. html †¢http://dictionary. reference. com/browse/philosophy%20? s=t †¢http://ancienthistory. about. com/cs/people/p/aristotle. htm †¢http://ancienthistory. about. com/od/platoprofile/p/Plato. htm †¢http://ancienthistory. about. com/od/socratesbio/p/Socrates. htm †¢http://www. historyforkids. org/learn/greeks/philosophy/ †¢http://webspace. ship. edu/cgboer/athenians. html †¢http://webspace. ship. edu/cgboer/greeks. html †¢http://philosophy. gr/ †¢http://philosophy. gr/hellinistic/cynics. htm †¢http://www. newworldencyclopedia. org/entry/Greek_philosophy,_A ncient †¢http://www. livius. org/gi-gr/greeks/philosophers. html †¢http://www. historyforkids. org/learn/greeks/philosophy/ †¢http://www. historyforkids. org/learn/philosophy/epicureans. htm †¢http://www. iep. utm. edu/stoicmind/ †¢http://www. iep. utm. edu/skepanci/.

Science Lab- Green House Earth essays

Science Lab- Green House Earth essays Problem: To determine what surface and color best obsorbs heat. 2 plastic hemispheres with tops a bases Safety Percautions: Be sure to keep water from contacting any part of the lamp assembly. Hypothesis: By using all the instruments givin to us, we will be able to figure out what surface and color best obsorbs heat. I think that the dark hard surface will obsorb more. Procedure: First, you have to set up plastic hemisphere with soil and water, thermometers, and a heat lamp(look at figure 2) Then you position the bulb of the heat lamp 20 cm above the hemispheres as shown in the diagram, being sure that the energy from the lamp is divided evenly between the two hemispheres. We had to work in two different groups, group A and group B. Our teacher gave us the groups. Both group A and group B will follow the same procedure for this first step. When temperature equilibrium has been reached, we had to record the beginning temperature for the soil and water and record these values under time 0 in the Data Table on the other page. Then, you turn on the lamp and record the soil and water temperatures every minute for 10 min. And we had to be sure the hempishperes are not covered. After the 10 min, we turned off the lamp and removed it from the area near the hemishperes. Then we had to draw a graph of the data on the graph grid provided. The time goes on the horizontal axis. Theory and Discussion: My hypthesis was correct, the dark rough soil obsorbed more energy then the water did. This is because dark rough surfaces obsorb more light energy then light smooth surfaces. Doing this lab helped my goup and I learn how dark colors obsorb a lot more heat then the light surfaces did. And after the 10 min. when we ...

The Twin Issues of Climate Change and Global Warming Essay

The Twin Issues of Climate Change and Global Warming - Essay Example    In effect, it is crucial to highlight the important role that an increment in fuel prices will play towards achieving these objectives to thus crucial and important population that is aware of global warming and climate change. For this reason, I addressed this open letter to the citizens of the United States. I believe that we have all heard the adage that "desperate times call for desperate measures." In our endeavor and the quest to satisfy the most basic of human needs, we face a momentous challenge on our environment and other essential components of human life. In line with this, we cannot live oblivious to the fact that some activities that we engaged in can bring untoward effects to our lives. In effect, such activities required urgent action in order to converse the world for future generations. You may be wondering about the motive behind this letter. However, I need to explain the intention behind this letter before I support my argument. First, how many times have we heard or read about the term global warming today on any form of media? In addition, what proactive measures were are taking to ensure that we maintain an environment that was safe for current and future living organisms? Besides, who amongst us today would not wish to experience new approaches that were safe and innovative and solved human kinds problems? I believe your guess is as good as mine with regard to all these questions. The underlying issue in this letter regards the divisive and emotive issue surrounding increasing of fuel prices. In this case, the issue has revolved around two opposing sides with each side putting up strong arguments for their cases.  Ã‚  On one hand, those proposing an increment in fuel prices argue about the economic, social, and environmental benefits arising from the increase.

Logistics and Supply Chain Management Essay Example | Topics and Well Written Essays - 2500 words

Logistics and Supply Chain Management - Essay Example It studies how it can be improved and gives recommendations. Since Zara is one of the industry leaders and has one of the best supply chains, it required fewer recommendations for improvement. Finally, the paper analyzes the location of the company’s plants and distribution centers to see whether they are optimal. In Zara’s case, they are in the short run but may cause problems in the long run. Zara is a Spanish flagship store of the Inditex Group and a key player in the European fashion retail market. It started operations in 1975 by opening its first store in La Coruna and since then has been operating as a fast fashion company. It is one of the largest brands, by the Inditex Fashion Retail Group, that has 723 stores in 56 countries making sales of Euro 3.8 billion (India Supply Chain Council, 2006). Its business model is simple; it imitates fashion off the runway and distributes it to the customers in the shortest time possible, even before designers themselves can reach the customers. Therefore, it has shorter lead times, more styles but scarce supply of these styles. To manage this kind of efficiency, Zara’s supply chain management must be efficient and that, it is. Zara uses a vertical supply chain management system, one of the best in the industry that allows it to implement its business model of fast fashion effectively. Zara’s position is an industry leader in the fashion retail market. It has a very high product turnover – it produces more than 11,000 products annually. It caters to the trendy, middle class man and woman of ages 14 to 35. The mother buys Zara because it is affordable and the daughter buys from Zara because it is trendy (Dutta, 2002). This paper will study Zara in the light of its Logistics and Supply Chain Management. It will be broken down into four main parts. First of all, the importance of measuring the performance of Zara’s Supply Chain will be analyzed. Secondly, key performance indicators or KPIs will

Development of Adult Education Research Paper Example | Topics and Well Written Essays - 1500 words

Development of Adult Education - Research Paper Example Development of Adult Education He defined that educational learning that is reflective in nature was better obtained through meaningful experiments. On the other hand, the development psychology theory defines that adult are psychologically not the same to normal post-adolescent college students. Therefore, it is pertinent that the theories of Erikson, Havighurst, Kolhberg, Gilligan, Magolda and Bronfenbrenner be taken into consideration while dealing with adults. Ultimately, the theory of critical learning has it that sociological analysis of education holds that learning institutions are considered hazardous to the social life of individuals. Most of the people who go to school usually end up oppressed, and this is worsened in the case of an adult amidst teenagers. In this process, the adult are tough so that they may bring new changes to the society through a transformational model engineered by Lindeman. The above three theories explained are crucial in the process of understanding adult development. Based on cross theory, adult learners employ both formal and informal system of learning, in which they face serious predicaments. These issues are usually addressed by the CAL model, which is essential in linguistics. It has also been identified that dealing with adults largely depends how they passed the eight psychological stages of development proposed by Erikson (44). According to him, all the stages are crucial since they either impact an individual positively or negatively. The 8 stages range from toddler to late adulthood. Say during the life course of an individual, school age, one underwent an extremely hard time making him or she ingrains a negative attitude in oneself on education. For such a person, it will be hard for him, or her, to successfully undergo adulthood education. This is because the individual will continue suffering the effects of what he or she pass, anytime t he word education comes across. This will not be the case for an individual who never had problems during school age; he or she will be ready to learn because he has a positive attitude toward education. For adults to learn appropriately, a rather close relationship should be developed between them and their teachers. Through this, they will be able to share different experiences that they underwent through their learning process. This will make it easier for the teacher to assist them whenever necessary. Both teachers and learners should understand that, for the process of learning to be successful, a proper balancing between the needs for the learner and that of the learning process should be balanced appropriately. The famous Pedagogy wrote by Freire had it that there should be a mutual relationship between student, teacher and the society. In the light to the above ideology, it was discovered that since the oppression in schools is majorly contribute by teachers, thy also have t he power to make schools a better place. With the creation of a conducive atmosphere, many adult and normal students will find it easy to learn, since there will be better co-operation. With reference to the theory of experimental learning, it has been noted by Fosnot that people get to gain

Of mice and men Film Essay Example for Free

Of mice and men Film Essay Of mice and men is a very touching film of hopes dreams and friendship. Adapted from the novel by John Steinbeck. The film is about two friends, Lennie and George, with a dream of great times with their own land and house. But there is a another story intertwined with theirs, about what people think of women. The two stories together will hold you in an array of emotions from joy to sorrow, and pride to guilt. This film if full of brilliant acting and meaningful uses of light and props. Of the two stories we will look at the one about women. We open the film with a man sitting in the shadows. Little light is coming in through the slits in the wood he is leaning on. He looks depressed and upset and bows his head as if hes trying to recall his memories of what went wrong to lead to this depression. And then we are suddenly in a field with early evening light filling a beautiful landscape, the main focus of our attention is of the woman running across the picture, shes white with brown hair wearing a torn red dress. As she runs we can see shes trying to run away form something or somebody, shes crying and the only sound we hear is her distressed breathing like she wants to cry but is holding the tears back. She looks like she has been attacked, although the dress is torn we only see a petty coat and not any flesh so this suggests that it might not have been sexual. But we cant really say for sure. The red dress represents passion so this says it could be sexual. We the see the two main characters running so we now think that they are connected to this. We never see this woman again in the whole of the story. The next woman we find is first only known as Curlys wife. She first comes into the story when she enters the bunkhouse where Lennie and George have only just arrived and are unpacking. Shes wearing a flowery dress which could be seen as innocent as it is cool colours and doesnt reveal much of her figure. Her hair is also in a very feminine style again to show innocence. Im looking for curly she says, almost as if she needs an excuse for being there. But also at the same time using it in an almost flirty sort of way trying to see how the new boys will react. He was in here a minute ago, but he left George replies cutting off that conversation. He hasnt stopped staring at her since she entered but not in a flattering way. We know he is a cautious person and he is almost looking at her trying to spot any type of threat. Especially as when Curly was in here he wasnt particularly nice. So his wife, even if she isnt like him in character, can still get him into trouble. Well I guess I better look some place else she says turning to face the door, only not to leave, just so the light shines on her from outside, showing off her figure. We now know that this girl is just one big flirt and George can see that. He wants her to leave as its the only thing that can happen to stop this tension, he cant leave with Lennie as they have no excuse to. Eventually after some more flirty lines she leaves. Through this scene we have been introduced to the only other woman in the film and we know shes a flirt and danger even if her image suggest otherwise at times. The camera reinforces this along with what she does. It starts with full body shots at the beginning of the scene and as she gets more flirtatious the shots concentrate on her upper body, then just her face, the attention is on her a lot of the time. The next scene with Curlys wife is in a barn as George takes a mule in. As he calls out for the stable buck she answers instead and comes half way over to some bags of hay. Shes in another flowery dress, again trying to portray innocence be we know that she is anything but innocent. This time she is also holding a book, possibly a story or maybe a diary, either suggest that maybe she isnt as much of the tart as we first thought and that she enjoys reading. Once again she tries to start a conversation, but George is still cautious of her and ignores her, concentrating on the mule. So to try to entice him she starts to once again flirt, as she sits on the bags of hay she leans back a little defining her chest. Her dress has ridden up revealing quite a bit of her leg, she pats the seat next to her trying to get him to come over. But still he just ignores her so she shouts. come over here and talk to me! he gets up and walks over to her. She calms down now she has her way. So she flirts to get her way most of the time but what we really want to know is if she really after a conversation or whether she only wants a cheap thrill like she has implied. All we have seen of her is her flirting and even now as hes come over to talk she is leaning against a pole like a lap dancer, asking about whether he has a sweetheart back home. We can almost certainly say that she is only after one thing. But then some thing happens that maybe changes our perspective of her. Her husband comes in. He ask whats going on and she says nothing I wasnt talking to you. he replies get back in the house. you dont own me curly. She says he now comes close to her and says in a way that seems like he might hit her I said go. And so she does. In this brief 2 minute talk we can see her relationship with her husband isnt a good one but he had just caught her with another man so maybe he can justify his anger. In this scene we have seen that Curlys wife is as we thought very flirty but that her relationship with her husband might cause this. She next walks into shot again in a flowery dress with a book as Lennie and George are hard at work in a field. In the scene before this Lennie and Curly have a fight. Lennie ends up with a bruised and scratched face and Curly gets a broken hand. Hi. she says, this is given a glance but they dont reply or give any recognition. sure is hot out here to day. She trys again to get conversation going. But again they dont care and keep on working. So she trys again. I said it sure is hot out here. why dont you go back to your house we dont want no trouble. Says George in a way that says I know I cant force you but I dont want you here. This is of course because of what Curly did. She is taken aback by this, she is used to being ignored but not told to leave by anyone other than her husband. I just want some one to talk to. She says. you got a husband, go talk to him George replies. yeah I got a husband. She says almost in a disappointed way. She then asks how Curly got his hand broken. To which George lies and says he got his hand caught in a machine. But this doesnt fool her so seeking an answer she asks Lennie who she knows wont have the mental capacity to make up a lie. how did you get those scratches on your face? she asks. Lennie looks to George and then looks away saying, he got it caught in a machine. He answers. is that so? She says with a look that is trying to work out how Lennie thinks. Almost as if she is concerned for him. She then quietly leaves. In this scene we begin to see that she isnt stupid she can work things out. Also that she doesnt like Curly and being married to him. The possibility that all she wants is some one to talk to is again present. In her penultimate scene we change our whole opinion of Curlys wife. Its set at night as Lennie and George are returning to the bunk house. Most of the other men are still in town spending their money in a whore house on girls and drink. Just as they are about to enter the bunk house Curlys wife comes out of the shadows looking upset and as if she has been crying. is curly back yet? she asks. no. says George knowing that Curly could very well be with another woman right now. She then says how Curly broke her records and we finally see a frail side of her caused by the fact her husband is now out possibly with another woman, he doesnt even talk to his wife, he doesnt even leave her with some measly records to listen to. We are shoved into feeling sorry for this poor girl and guilty that we thought she was just after a cheap thrill, when all she really wanted was someone to talk too. We get to see the womans frail side in this scene and we finally see her true motivation for the way she is, we see that she is very hurt and is just good at putting a brave face on things. In her last scene Curlys wife walks into a barn where Lennie has just accidentally killed a puppy. As she comes over he hides away and says how she would get him in trouble. whats wrong with me? she shouts at him as he rejects her company. Lennie doesnt see her as a sex object and so he doesnt see any danger in her although he is slightly attracted to her. So he opens up a little to her and in turn she opens up and finally we see her shed this mask that only shows her body and the fact that she is just a woman and should be treated as just some object. But now Lennie is sitting there talking to her as an equal and this is the sort of interaction with other people that she has tried to get through out the whole film. We find out as she opens up that she wanted to be an actress and she had plans to go to the theatre or Broadway and be an actress. Lennie is going on about tending the rabbits and not really listening but still Curlys wife doesnt care and talks about her dreams still. Eventually they do start listening to each other, and they find a common like for soft things. She lets him feel her hair, and then we see her open up in another way. Usually Curly is only interested in one thing, quick sex to satisfy him with no feelings involved, but here with Lennie she is being appreciated with close touch. She likes the fact he is being gentle and soft only after the simple pleasure of being able to stroke her hair. But he is a child in a strong mans body and he doesnt let go of her hair when she asks him to stop as he gets a little rough, and she screams, he grabs her and gags her, he only wants her to stop shouting but as he lays her back down we see that he has broken her neck. She lies silently in a pool of light on the hay as Lennie runs in fear. For a brief second we saw this beautiful woman blossom and show her true self and now she is gone. Though this film we see a progressing way in how men picture women. In the bunk house scene all we see is a flirty woman, and we are focused on her body. In the second scene we get another showing of this but at the end we see her giving in to her husband and maybe a suggestion of how he treats her. Next we see her being ignored by the boys, they consider her trouble even thought its not directly her fault, also we see a bit of her intelligence and that she isnt that stupid. Then finally we see her frailty and that she is not just a pair of breasts on legs, she has feeling as well as a mind and emotions. We can conclude that because of the way men see her, causes her to flirt as its the only way to get any attention. Because she doesnt get the conversation and interaction from Curly she turns else where and flirting is the only way to get that interaction she wants. In the last scene we see her mind, her dreams, opinions and thoughts. we see the side of her that has been ignored by every one just because shes a woman. Through the whole film we dont even get to know her name. But with Lennie these barriers are broken as he doesnt understand them and so she can open up and talk to this person. Even though he might not be listening he isnt blocking her out because she a woman and she gets the interaction that she wants and that she has been searching for. Then finally she dies and we are left with a memory of a woman that showed her mind to us and how she was no longer just a body to be looked at by men. But for a brief moment considered as an individual person.

Food Safety And Food Quality Assurance Environmental Sciences Essay

Food Safety And Food Quality Assurance Environmental Sciences Essay The food industry/fish industry has a moral and legal obligation to produce safe and wholesome food. Food firm management must continue to be the first line of defense in the production and manufacture of safe food (Alli, 2004). The first step in food safety program is a food factory safety program is the establishment of a safety committee with full authority for assuring the manufacture of safe and wholesomeness of food. The second major safety compound which is important in any food firm are the methods on the food processing. The food plant must have strict operating specifications or every unit operation in the plant. Every food plant has different operating specification even it plant processes same products. The third key safety factor in every food firm is the hazards associated with the various commodities and/or the various processes or usually methods in use. Raw material that are use in food plant should be monitor by the quality assurance team. It is to reduce hazard on raw material. Furthermore, on food processing plant, hazard may also appear. Biological, chemical, and physical hazards can cause seafood-related illnesses. Biological hazards include Clostridium botulinum, Listeria monocytogenes, Salmonella, E. coli, and pathogenic staphylococcus. Chemical hazards include compounds such as Pb, carcinogenic compound, , which can cause illness from long-term exposure. Physical hazards include foreign objects in food that can cause harm when eaten, such as glass, hair, , or metal fragments. Food Safety and Food Quality Assurance Food safety is the assurance that food will not cause harm to the consumer when it is prepared and eaten according to its intended use. The assurance that food may not cause harm, injury, or illness is determined by (1) all harmful substances present in the food have been eliminated or prevented from exceeding the acceptable level; and (2) the food has been prepared, handled, and stored under controlled and sanitary conditions in conformance with practices prescribed by government regulation (Alli, 2004). The fish industry, like many other industries, has used basic quality control programs, and more complex quality assurance programs and quality management systems, in its efforts to achieve food quality. Good Manufacturing Practices (GMP), Sanitation Standard Operating Procedures (SSOP) and the Hazard Analytical Critical Control Point (HCCP) system can be integrated into a food industry, quality management system, or inspection and monitoring materials, products, and processes for food safety hazards can be part of quality control program. On implementation of food safety system, food industry policies should be based on food safety regulation. There are some food safety regulations as follows: Food safety regulation 1995 in the UK These regulations came into force on 15 September 1995 and implement the provision of the directive on hygiene foodstuff (93/94/EEC; section 12.3.2.1.) except for those which relate to temperature control (section 12.5.4.). This main feature of regulations is that proprietors are required to identify and control food safety risk at all stages in preparation and selling of food using hazard analysis (Forshyte and Hayes, 1998). This must be done according to the following principles: Analysis of potential food hazards in the operation. Identification of those points in the operation where hazards, may occur. Deciding which the points identified is critical to ensuring food safety. Identifying and implementing effective control and monitoring procedures at those critical points. Review of the system periodically and whenever the operation changes. Fish, shellfish and fishery products legislation in the EC Legislation Council Directive 91/493/EEC legislation is concerned directly with fish. This legislation aims to harmonize measures for the handling and treatment of all fish and shellfish at all stages up to retailing. There is the usual detail in food standards, this covering factory vessels and fish processing factory. The Council Directive, 91/492/EEC lays down health conditions for the production and placing on the market of live bivalve mollusks (Foshyte and Hayes, 1998). The commission Decision 93/51/EEC on the microbiological criteria applicable to the production of cooked crustaceans and mollusks shellfish is summarized in Table 1.1. The Good Manufacturing Practices (GMP) regulation in the USA According to Forsythe and Hayes (1998), this regulation is divided into four subparts, as follows: General provision: This part is concerning personnel. No person affected by disease or boils, sores, infected wounds, etc, may work in food premises where there is a reasonable possibly of food being contaminated or other personnel infected. Building and facilities: the need for clean surround to factories is stressed so that pets are not attracted and food not contaminated. Factories should be constructed so that cleaning is facilitated and adequate working and storage space should be provided. Floors, walls and ceilings should be constructed well to allow for adequate cleaning, duct and pipes should not be suspended working areas where drip or condensate may contaminate food materials or food contact surfaces. Table 1.1. The examples bacteriological standards for fish products in several countries Countries Standard Product Microorganism Level EU Fish products 91/493/EEC and Commision Decision 93/51/EEC Cooked crustaceans and molluscan shellfish Salmonella Absent in 25 g, n=5, c=0 Cooked crustaceans and molluscan shellfish Other pathogens and toxin thereof Not to be present in quantities such as to affect health Whole products Mesophilic aerobic bacteria m = 10000 M = 100000 n = 5 c = 2 Crab meat Mesophilic aerobic bacteria m = 100000 M = 1000000 n = 5 c = 2 France Sliced fish, crumbed or not; fresh fish fillets, refrigerated Total aerobes Faecal coliforms S. aureus Anaerobic shulphite reducer Salmonella 50.000 per g max 10 per g max 100 per g max 2 per g max Absent in 25 g Shellfish, bivalves, urchins live Faecal coliforms Faecal streptococci Samonellas 300 per 100 ml max 2500 per 100 ml max Absent in 25 g USA Marshall (1986) Crab meat, fresh or frozen E. coli 4 per g max Shrimps, raw, breaded Viable aerobic bacteria 100000 per g max E. coli 4 per g max S. aureus 100 per g max Japan Marshall (1986) Frozen foods: Require only thawing before consumsption Total viable bacteria Coliforms Absent in 1 g Heated before consumption Total viable bacteria Coliforms Absent in 1 g Raw oyster Total viable bacteria;E coli 50000 per g max; 230 per 100 g max Korea Anon (1995) Fish product Number of bacteria Coliform E coli Negative for sterilized products Exection half-processed surimi Negative for half-processed surimi Source: Forsythe and Hayes (1998)Equipment. This subpart includes a very brief description of desirable features in the design and construction of food processing equipment. Design and construction must ensure that contamination of food with lubricants, fuel, metal fragments, etc. are avoided. Food contact surfaces must be corrosion resistant, made of non-toxic materials and be resistant to the action of any food materials. Production and process control. This subpart includes regulations for the inspection, cleaning and storage of raw materials, restrictions on the use of food premises, and equipment and regulations on the cleaning and maintenance of equipment. International implementation of HACCP concept HACCP is internationally accepted as the major means of assuring food safety as promoted by the Codex Alimentarius Commission (Forsythe and Hayes, 1998). The joint FAO/WHO Codex Alimentarius Commission describes the steps needed to implement the HACCP system. Before implementing a company should have minimum hygiene measures, for example, according to the Codex General Principles of Food Hygiene, the appropriate Codex Codes of Practice and appropriate food safety legislation. These requirements should be well specified and documented, fully operational and verified in order to facilitate the successful application and implementation of HACCP (National Board of Experts-HACCP, 2002 in Plaggenhoef et al., 2002 ) The HACCP system which is science based and systematic, identifies specific hazards and measures for their control to ensure the safety of food. HACCP is a tool to assess hazards and establish control systems that focus on prevention rather than relying mainly on end-product testing (FAO/WHO, 1997). e. ISO 22000:2005 ISO 22000 is international standard that was prepared by Technical Committee ISO/TC 34, Food products. This International Standard specifies the requirements for a food safety management system that combines the fol owing general y recognized key elements to ensure food safety along the food chain, up to the point of final consumption: interactive communication, system management, prerequisite programs, and HACCP principles. This International Standard integrates the principles of the Hazard Analysis and Critical Control Point (HACCP) system and application steps developed by the Codex Alimentarius Commission. By means of auditable requirements, it combines the HACCP plan with prerequisite programs (PRPs). This International Standard specifies requirements for a food safety management system where an organization in the food chain needs to demonstrate its ability to control food safety hazards in order to ensure that food is safe at the time of human consumption (ISO, 2005). 1.3. The Relationship between Prerequisite program, HACCP (Hazard Analysis Critical Control Points) and TQM (Total Quality Management) Fish plants that operate with HACCP system will have the required prerequisite programs that includes GMP and some industry sectors in Indonesia include SSOP. The fish processing plants that do not have HACCP system, the GMP remains essential for addressing food safety. It is more appropriate for the HACCP prerequisite to be used instead of the basic GMP. The prerequisite programs provides more comprehensive coverage of the requirements relating to conditions and activities in a food plant than will the GMP. In food plants that do not operate with HACCP systems but have implemented the ISO 9001 Quality Management Systems standard, as a minimum the GMP should be part of the applicable regulatory requirements of the standard (Alli, 2004). All food plants need to develop and implement a program of GMP to address food safety requirement. Food plants that develop and implement the HACCP systems to address food safety also need to develop and implement the HACCP prerequisite programs. The activities for GMP or the HACCP prerequisite programs that are developed at a food plant should be documented as SOP. In addition, where monitoring, inspection, or testing is carried out as part of the programs, records should be kept as evidence that these activities are actually performed (Alli, 2004). HACCP is an approach to hygienic food production by prevention of problem (Forsythe and Hayes, 1998). The hazards analysis portion of HACCP involves a systematic study of the ingredients, the food product, the conditions of processing, handling, storage, packaging, distribution and consumer use (Pearson and Dutson, 1999). TQM is an effort for continuously improving the quality of all process, products, and services through universal participation of all employees, that lead greater customer satisfaction and loyality, and improved business results (Sarvadan, 1992 in Pearson and Dutson, 1999). In many cases, the TQM approach has produced remarkable changes in how management and employees envision and interpret quality. The TQM approach requires a company to develop a strategy, involving all levels and functions of the company, which focuses on satisfying the customer. Everyone involved TQM will have a new mind set towards quality. Consequently, there will be a drastic and permanent change in the culture of company, giving company personnel an entirely new focus on quality improvement (Pearson and Dutson, 1999). The combination of TQM and HAACP, include GMP and SSOP, provides a total systems approach to food processing, encompassing the elements of food safety, food quality and food productivity (NFPA, 1992). This combine method will stress commitment, education, preventive and corrective action, statistical control, record keeping, verification and teamwork (Pearson and Dutson, 1999). TQM teams, responsible for developing and implementing HACCP, should comprise representatives from a variety of discipline and workers from all levels. This type of diversity assures effective evaluation of all areas that may have an impact on safe food processing (Pearson and Dutson, 1999). Summary In summary, hazard in food industry may be includes biological, physical, and microbiological aspects. They present new challenges to the industry and they must be eliminated during the manufacture of safe and wholesomeness food. All finished product must be audited for quality assurance through the marketing channel, and every plant must establish quality assurance department with full authority to uphold the policies and standards of food firm for the production of safe and safety. High quality foods that are safe are in great demand and the technology is available to any food firm to live well within the rules and regulation for the production of foods that are most acceptable.